scratching CKD-associated pruritus can contribute to:
* Scratches
* Open sores
* Skin irritation
* Secondary infections
This is another reason persistent itching should be treated rather than ignored.
If unexplained sores appear without scratching—or wounds are not healing normally—other causes such as diabetes, circulation problems, infection, or dermatological conditions also need to be considered.
## Skin Symptoms Usually Aren’t the First Sign
One of the most important facts about chronic kidney disease is that it is often **silent in its early stages**.
A person can lose significant kidney function without noticing obvious symptoms.
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